Fiji born and England wing Semesa Rokoduguni has been ruled out of the autumn international test against South Africa with a hip injury.
Harlequins' Marland Yarde has been called up as a replacement.
Serving soldier Rokoduguni made his debut against New Zealand, but picked up an injury in the 24‑21 defeat at Twickenham.
England will play South Africa at 3.30am this Sunday.